A Search Engine for mRNA: Algorithm Identifies Optimal Sequences to Improve COVID Vaccines
- lindsayvicars
- May 19, 2023
- 1 min read
Updated: Apr 2
From the University of Rochester Medical Center Newsroom:
Messenger RNA vaccines proved their worth in the COVID pandemic, and new software stands to make the already transformative technology even more powerful.
Scientists developed an algorithm to identify the most stable, efficient mRNA sequences for vaccines. Tests show that the algorithm-derived mRNAs resist deterioration longer, produce more COVID spike protein, and dramatically increase antibody levels in mice compared to currently used mRNA vaccines. The results were reported in the journal Nature.
Study authors believe their tool will be valuable to companies that make mRNA vaccines and to research teams developing mRNA-based therapies for genetic disorders, cancer and a plethora of other diseases that can be treated by using mRNA to express a needed protein. (click here to keep reading)
Author: Emily Boynton
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